Speaker: Professor Andrea Yool, Professor of Physiology, University of Adelaide FHMS Sciences; Director of Research Education, FHMS; Director, Aquaporin Physiology and Drug Discovery Research Program
Title: Drug design for aquaporin channels involved in cancer cell motility
Chair: Dr Jenny Hardingham, Principal Medical Scientist, Solid Tumour Group, Haematology-Oncology Department Level 1 BHI, TQEH. [email protected]
Speaker biography: Andrea Yool completed her PhD at University of California Santa Barbara and postdoctoral fellowships at the Scripps Clinic (San Diego) and Stanford University (Palo Alto, USA) before joining academic staff in Physiology at the University of Arizona (Tucson, USA) in 1993. In 2007 she relocated with family to South Australia as Professor and Head of Physiology at The University of Adelaide. More than a decade of research by Yool and her team on human aquaporin-1 channels has defined the permeation and gating properties of these channels, novel pharmacological modulators, and essential roles in migration and metastasis in aggressive cancers. Collaborative work with Dr Jenny Hardingham and Professor Tim Price at the BHI, TQEH is pioneering the translational potential of the aquaporin drugs in vivo.
