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Dr Cher-Rin Chong is a clinical pharmacist who was awarded her PhD in 2017. Read about her PhD research, completed under the supervision of Professor John Horowitz and Associate Professor Betty Sallustio, in a story by The Hospital Research Foundation.


In 2015 Cher-Rin was awarded the prestigious Oxford Nuffield Medical Fellowship to undertake 2 years of postdoctoral research at the University of Oxford, England. In Oxford she will work with Professor Kieran Clarke and her research group in the Department of Physiology, Anatomy & Genetics. Cher-Rin left for Oxford in May 2016 having just submitted her PhD thesis.


 


Cher-Rin has recently been awarded an NHMRC Peter Doherty Biomedical Early Career Fellowship (#1162356) for 2019-2022. Her project “Novel strategy to prevent cardiovascular complications in diabetes: the role of poly(ADP-ribose) polymerase-1 inhibition”. Brief description of project:


The diabetic heart is characterized by inflammation and low energy status, resulting in heart failure, impaired vessel function and blood clot formation.  Previous studies found that such processes involve the uncontrolled over-activation of an enzyme called PARP-1, usually responsible for repairing damaged DNA. This project will seek to better understand the extent to which PARP-1 is activated, and the impact of its inhibition on vascular, platelet and cardiac metabolism in diabetes.


Cher-Rin’s PhD research focussed on improving the efficiency of the heart in two ways:

  • maximising the income of energy (by using a heart medication called perhexiline), and
  • reducing energy expenditures during crisis

Apart from her PhD thesis, Cher-Rin has also been involved in the research of Tako-tsubo cardiomyopathy (TTC). In particular, she is interested in antidepressants that may be associated with TTC and the impact of blood pressure changes during the acute stage of TTC. Additionally, Cher-Rin is also passionate about the further development of the pharmacy profession through education, experience and research. She wishes to be actively involved in the pharmacy profession in order to continue to improve patient outcomes. To help achieve this Cher-Rin is involved in a number of pharmacy-practice projects promoting the quality use of medicines.

Qualifications

Cher-Rin’s PhD thesis “A pharmacological approach towards myocardial protection: new perspectives in acute and chronic cardiac disease” was awarded in 2017.

Bachelor of Pharmacy, University of South Australia

Professional Associations

2015 – present: Steering Committee (Advisory and Governance), Young Professionals Group (YPG), Department of Health, Government of South Australia.

2015 – present: Invited committee member, Committee of Specialty Practice – Cardiology, The Society of Hospital Pharmacists of Australia  

2013 – present: Affiliate member, Cardiac Society of Australia and New Zealand (CSANZ)

2013 – present: Member, Young Professionals Group, Department of Health, Government of South Australia.

2011 – 2015: The Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists

2008 – present: The Society of Hospital Pharmacists of Australia (SA/NT branch), Committee Member from 2011 – 2015.

 

2015: Oxford Nuffield Medical Fellowship

2014: Cardiac Society of Australia and New Zealand (CSANZ) Travelling Fellowship to American Heart Association Scientific Sessions at Chicago

2014: CSANZ Affiliate Clinical Development Award

2013: CSANZ Travelling Fellowship to American Heart Association Scientific Sessions at Dallas, Texas

2013: Professional Development Grant, Young Professional Group, South Australian Department of Health

2011-2013: Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (ASCEPT) student travel grants

2012-2015: NHMRC Dora Lush Biomedical Research Postgraduate Scholarship

 

Cher-Rin is a Committee Member of the Cardiology Committee of Speciality Pratice, Society of Hospital Pharmacists of Australia.

Cher-Rin and her supervisor Prof John Horowitz were interviewed for an article in “SpecialistUpdates – Cardiology” in August 2014.

You can also read about her research in a story by The Hospital Research Foundation.