- Key Publications
Our mission is to conduct innovative population and clinical research studies and produce the evidence for initiatives that promote prevention, lead to early detection and better management of disease, and improve quality of life, well-being and mental health. Observatory research also investigates the interaction of health services with patients to identify opportunities that lead to more effective health care and management, and that will maximise health outcomes. We have research opportunities available to anyone interested in clinical, epidemiological or population research, as well as health services research, health economics or mathematical modelling.
Postgraduate Student Projects
We are always looking for exceptional students to undertake research towards Honours or PhD degrees in any of our projects. We welcome interest from students in medicine, nursing or allied health professions or from doctors-in-training who need to complete research projects as part of their qualifications. Many former students have undertaken research projects that have culminated in presentations at national and international meetings and resulted in peer-reviewed journals publications.
Additional Current Postgraduate Students
Graham Tucker: Statistical and methodological aspects of assessment of health-related quality of life (part-time).
Hannah Newell: Sleep disorders and schizophrenia
Yohannes Melaku: Macronutrients, bone mineral density and osteoporosis (international student)
Joule Li: “Grip strength and incident diabetes”
Recent Student Alumni
Natalie Cutri: “Clinical Studies of Patients with Acute Coronary Syndrome in the Absence of Obstructive Coronary Artery Disease”. Natalie is currently a Clinical Research Associate with CPR Pharma Services.
Mark Dodd: “Economic aspects of the health impact of obesity”. Mark is currently a Lecturer in the School of Economics at the University of Adelaide
Solomon Yu: “Cytokines, Adiposity and Sarcopenia in the elderly”. Solomon is currently a Consultant Physician, Aged & Extended Care Services at The Queen Elizabeth Hospital.
Sarah Appleton: “Epidemiological investigation of the role of phenotype in the association of obesity and asthma”. Sarah is current a Post-Doctoral Research Fellow within The Health Observatory / Freemason’s Centre for Men’s health, and is based at the Basil Hetzel Institute, TQEH and SAHMRI, Adelaide.
Sam Biermann: “Health literacy and stroke risk factors and behaviour”. Sam is currently undertaking further study.
Simone Orlowski: “Social connectedness, personality, and presentation at ED: Establishing the validity of the Social Connectedness Questionnaire”. Simone is currently undertaking a PhD at Flinders University.
Justyna Pollock: “Diet, sleep and depression interactions”. Justyna is currently undertaking a PhD at the University of Adelaide and is based at the Basil Hetzel Institute, TQEH.
Emma Dunstan: “Epidemiological and genetic investigation of Giant Cell Arteritis in South Australia”
Obstructive sleep apnea (OSA) is common, and likely to exert a negative effect on a number of areas including cardiac, metabolic, renal, cognition and mood. As other risk factors (such as smoking and hypertension) reduce in significance due to public health campaigns or medications, OSA will increase in importance as a general risk factor for adverse outcomes and multi-morbidity.
The North West Adelaide Health Study (NWAHS) is a representative biomedical population cohort study of approximately 4000 adults aged 18 years and over recruited from the northern and western regions of Adelaide, that commenced in 2000, with multiple follow-up stages since then.
There are opportunities to undertake analysis of musculoskeletal data from the North West Adelaide Health Study (NWAHS). This established cohort study of 4000 individuals has collected musculoskeletal data on three occasions.
This Collaboration came into existence during the first half of 2014. It brings together many clinicians and modellers who have worked across Australia over the last 10-20 years. Cumberland.au recognises the importance and potential to apply the following to achieve reform in health: Systems thinking; Design thinking; Mathematical modelling (including the use of simulation), and Operations research.
These publications highlight the areas of research currently being undertaken by The Health Observatory.
This research examined a longitudinal cohort population showing how different clinical phenotypes have different health outcomes.
Appleton SL ,Wilson DH, Taylor AW, Adams RJ. Diabetes and cardiovascular disease outcomes in the metabolically healthy obese phenotype: a cohort study. Diabetes Care; 2013. 36(8): 2388-2394.
This paper extends our knowledge of what specific factors in OSA are associated with impaired glycemic control.
Appleton SL, Vakulin A, McEvoy RD, Wittert GA, Martin SA, Grant JF, Antic NA, Taylor AW, Catcheside PG, Adams RJ. Nocturnal hypoxemia and severe obstructive sleep apnea are associated with incident Type 2 diabetes in a population cohort of men. Journal of Clinical Sleep Medicine; 2015. 11(6): 609-614
This paper showed for the first time that health literacy influences diagnosis and management of obstructive sleep apnea (OSA).
Li JJ, Appleton SL, Wittert GA, Vakulin A, McEvoy RD, Antic NA, Adams RJ. The relationship between functional health literacy and obstructive sleep apnea and its related risk factors and comorbidities in a population cohort of men. Sleep; 2014. 37: 571-578
Murray CJ, …Hill C et al. Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet; 2012. 380: 2197-223.
Vos T,..Hill C, et al.. Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet; 2012. 380: 2163-96.
These last two 2 publications outline the global burden of disease from 1990-2010, for which Dr Catherine Hill contributed expertise on musculoskeletal disease. They have already been extensively cited with over 1500 and 100 citations respectively. These studies have demonstrated that global disease burden has continued to shift away from communicable to non-communicable diseases and from premature death to years lived with disability.
Funding since 2010
|Chief Investigators||Granting Body||Project Title||Type of Grant||Total Grant Amount||Funding Period|
|Hewitt A, Hill CL, Evans D, Merriman T, Morgan A, Smith K, McKelvie P, Martin J||NHMRC||Dissecting the great ophthalmic masquerade: The Global Giant Cell Arteritis Genomics Consortium||Project Grant #1068023||$569,927||2014 - 2015|
|Jones G, Cicuttini F, March L, Hill CL, Dore D||NHMRC||A randomised trial of zoledronic acid for osteoarthritis of the knee||Project Grant #1045415||$954,597||2013 - 2015|
|Wang Y, Cicuttini F, Tonkin A, Hill CL, Ding C||NHMRC||Does statin use have a disease modifying effect in symptomatic knee osteoarthritis? A multicentre randomised, double-blind, placebo-controlled trial||Project Grant #1048581||$971,020||2013 - 2015|
|Wittert G, Wilson D, Travision T, Adams R, Taylor A, McKinlay J, Jenkins A, Milne R, Hugo G, Atlantic E||NHMRC||Effect of sex steroids, inflammation, environmental and biopsychosocial factors on cardiometabolic disease risk in men||Project Grant #627227||$1,700,000||2010 - 2012|
|Daniel M, Hugo G, Paquet C, Taylor A, Cargo M, Adams R||NHMRC||Linking Place to Metabolic Syndrome via Behavioural and Psychosocial Antecedents: Levers for Public Health Intervention||Project Grant #631917||$545,000||2010 - 2012|
|Daniel M, Hugo G, Paquet C, Taylor A, Cargo M, Adams R||NHMRC||Linking Place to Metabolic Syndrome via Behavioural and Psychosocial Antecedents: Levers for Public Health Intervention||Partnership Grant #570150||$325,000||2010 - 2012|
|Hugo GJ, Wittert GA, Adams RJ, Cobiac L, Daniel M, Findlay CC, Taylor AW, Wilson DH, Winefield HR, Woollacott AL, Ruffin R||ARC||Australia's Baby Boomer Generation, Obesity and Work - Patterns, Causes and |
|Linkage Grant #LP0990065||$1,357,000||2009 - 2011|
|Mackay M, Adams R, Bean N||South Australian Government||The Promulgation of Operational Research, Systems Thinking and Design Thinking within the Australian Health Care Sector||Premier’s International Research Fund||$400,000||2015|
|Hoon E, Hill CL, Gill TK||Arthritis Australia||Developing a patient reported outcome measure in polymyalgia rheumatica||Grant||$10,000||2015
|Adams R, Jones G||Partners in Recovery||Pilot Project of Consumer centred care; developing an electronic communication, care and evaluation platform for Partners in Recovery||Grant||$100,000||2014|
|Shanahan EM, Hill CL, Gill TK||Arthritis Australia||Suprascapular nerve block for the treatment of adhesive capsulitis||Grant||$30,000||2014|
|Brown M, Hewitt A, Merriman T, Rischmueller M, Hill CL||Arthritis Australia||Genetics of Giant Cell Arteritis||Grant||$25,000||2013|
|Gill TK, Hill CL, Shanahan M, Allison D||Arthritis Australia||Pilot study of MRI in shoulder pain||Grant-in-Aid||$15,000||2012|
|Adams R, Bidargaddi N||Country Health SA||The Mental Health Observatory||$70,000||2012|
|Adams R, McEvoy D, Wittert G||ResMed Foundation||Investigating sleep apnea in a community-based sample of men||$50,000||2011
Sleep Health, Population Health, Health Services and Mental Health project collaborators
|Prof Gary Wittert, Dr Sean Martin, Dr Andrew Vincent||Freemason’s Centre for Men’s Health||University of Adelaide, SAHMRI||Adelaide||Australia|
|Prof Anne Taylor, Dr Zumin Shi||Population Research and Outcomes Study Unit||University of Adelaide, SAHMRI||Adelaide||Australia|
|Prof Doug McEvoy, A/Prof Nick Antic, Dr Peter Catcheside, Dr Andrew Vakulin||Adelaide Institute for Sleep Health||Flinders University||Adelaide||Australia|
|Prof Renuka Visvanathan, Dr Solomon Yu||Aged & Extended Care Services and the Adelaide Geriatrics Training and Research with Aged Care (G-TRAC)||The Queen Elizabeth Hospital||Adelaide||Australia|
|Prof Mark Daniel, Dr Catherine Paquet||Spatial Epidemiology & Evaluation Research Group||Sansom Institute for Health Research, University of South Australia||Adelaide||Australia|
|Prof Cherie Galletly, Dr Dennis Liu||Discipline of Psychiatry||University of Adelaide||Adelaide||Australia|
|Dr Niranjan Bidargaddi (Flinders University), Dr Geoff Schrader (Flinders University), Dr Jorg Strobel (Country Health SA)||Mental Health Observatory||Flinders University and Country Health SA||Adelaide||Australia|
|Mr Reg Harris||Country SA Primary Healthcare Network||South Australian Government||Adelaide||Australia|
|Dr Mark Mackay (Flinders University), Prof Nigel Bean (University of Adelaide), Prof Campbell Thompson (University of Adelaide), Prof Don Campbell (Monash University), Prof Jon Karnon (University of Adelaide), Prof Peter Taylor (University of Melbourne), Prof Terry Young (Brunel University, London), A/Prof Kathryn Zeitz (Central Adelaide Local Health Network)||Cumberland.au – The Australian Health Care Modelling and Systems Design Collaboration||Flinders University, University of Adelaide, Monash University, University of Melbourne, Brunel University (London), Central Adelaide Local Health Network||Adelaide, Melbourne, London||Australia and UK|
|Prof Ron Grunstein, Dr Angela D’Rozario||Centre for Translational Sleep and Circadian Neurobiology, Woolcock Institute of Medical Research||University of Sydney||Sydney||Australia|
|Dr Lisa Pont||Centre for Health Systems and Safety Research||Macquarie University||Sydney||Australia|
Musculoskeletal Conditions project collaborators
|A/Prof Michael Shanahan||Rheumatology Unit||Flinders University||Adelaide||Australia|
|A/Prof Susannah Proudman, Prof Les Cleland||Rheumatology Unit||Royal Adelaide Hospital||Adelaide||Australia|
|Prof David Findlay||Orthopaedics||University of Adelaide||Adelaide||Australia|
|Dr Domenic Thewlis, Dr Tash Stanton, Dr John Arnold||School of Health Sciences||University of South Australia||Adelaide||Australia|
|Prof Hylton Menz||La Trobe University||Melbourne||Australia|
|Prof Lyn March||University of Sydney||Sydney||Australia|
|Prof Flavia Cicuttini||Monash University||Melbourne||Australia|
|Prof Graeme Jones||Menzies Health Research Institute||Hobart||Australia|
|A/Prof Sarah Mackie, Prof Ann Morgan||Leeds University||Leeds||UK|
|Prof Matthew Brown (University of Queensland), Dr Alex Hewitt (University of Melbourne), Prof Ann Morgan (Leeds University, UK), Tony Merriman (University of Otago, NZ)||Australasian Genomics Recruitment Initiative in Australasia (AGRIA)||University of Queensland, University of Melbourne, Leeds University (UK), University of Otago (NZ)||Brisbane, Melbourne, Leeds, Dunedin||Australia, UK and New Zealand|