Speaker: Dr William Murray-Brown, Research Associate, Department of Rheumatology, Flinders Medical Centre
Title: Next generation histology in Rheumatoid Arthritis: Automated multi parameter microscopy and machine learning image analysis
Chair: Sue Lester, Chief Medical Scientist, Rheumatology Research Group, Level 2 BHI, TQEH
Speaker Biography: Dr William Murray-Brown is a Research Associate in the Rheumatology Department at Flinders University where he investigates the efficacy of currently available therapeutics in rheumatoid arthritis (RA), with a view to identifying biomarkers predictive of treatment response (a currently unmet clinical need in RA treatment). His research also seeks to identify novel therapeutic targets in RA through pharmaceutical collaborations. Dr Murray-Brown is also an Honorary Research Associate at the Olivia Newton John Cancer research centre in Melbourne, where he is developing an innovative multi-parameter fluorescence microscopy technique and automated computer analysis pipeline of pathogenic tissues in RA (featuring in today’s presentation) as well as investigating immunological adverse events to checkpoint inhibitor therapies.
Dr Murray-Brown graduated with his PhD from Imperial College London in 2011 and went on to work in the laboratories of Professor Costantino Pitzalis and Dr Michele Bombardieri at the William Harvey Research Institute, where he investigated T and B cell pathogenesis in the Sjogren’s syndrome and RA. As an early career researcher, Dr Murray-Brown has published in top rheumatology journals during his positions in London and here in Adelaide, he has contributed to the successful acquisition of large competitive funding applications helping generate $250,000 for the rheumatology department at Flinders University and his research has been recognised with a EULAR conference basic science award in 2015.