Speaker: Professor Stuart Brierley, NHMRC RD Wright Biomedical Fellow, Matthew Flinders Research Fellow in Gastrointestinal Neuroscience, Director of Visceral Pain Research Group, College of Medicine and Public Health, Centre for Neuroscience, Flinders University
Title: Visceral Sensation: From tarantula toxins to itchy colons
Chair: Professor Betty Sallustio, Principal Medical Scientist, Clinical Pharmacology Research Group, Level 2 BHI, TQEH
Speaker biography: Prof Brierley is an international leader on the different afferent classes innervating the gut and the bladder, the channels and receptors underlying their function and how this changes in acute and chronic pain. Prof Brierley has a proven track record in coordinating multi-faceted research programs for high-impact publications in journal such as Nature, Cell, Nature Communications, Gastroenterology, Gut, PNAS, JCI Insight, Pain, British Journal of Physiology and The Journal of Neuroscience. He also has invited reviews published in Nature Reviews Gastroenterology and Hepatology, Annual Reviews of Physiology, Gut, Trends in Biomedical Sciences, Journal of Physiology and The International Journal of Biochemistry & Cell Biology.
His recent collaborations with Industry partners identified the mechanism of pain relief of a new drug, linaclotide, in treating patient with Irritable Bowel Syndrome with Constipation (IBS-C). Linaclotide, a guanylate cyclase-C (GC-C) agonist is effective in relieving abdominal pain associated with IBS-C and is already available and registered for use by IBS-C patients in the USA and Europe.
For more information visit Stuart’s Flinders University profile.