NHMRC Partnership Project Grant for the PAMICO Project

April 01, 2021

A National Health and Medical Research Council Partnership Project Grant, providing $1,499,233 in funding over 3 years has been awarded for the PAMICO Project – Personalising Acute Myocardial Infarction Care to improve Outcomes. Chief Investigators for this project are:

CIA: Professor John Beltrame, The University of Adelaide and CALHN [photo, left]

CIB: Professor John Spertus, University of Missouri, USA

CIC: Associate Professor Rosanna Tavella, The University of Adelaide and CALHN [photo, right]

CID: Associate Professor Christopher Zeitz, The University of Adelaide and CALHN

CIE: Professor Gillian Harvey, Flinders University

The modern management of heart attacks has improved survival dramatically, however, not all patients receive the best care available, leading to variation in quality and health outcomes. The PAMICO Project (Personalising Acute Myocardial Infarction Care to improve Outcomes) aims to bridge this gap using sophisticated electronic data systems and integrated care teams to produce personalised clinical management pathways so that care is patient-centered and aligned with best practice.

Professor John Beltrame and Associate Professors Rosanna Tavella and Chris Zeitz are all members of the Translational Vascular Function Research Collaborative which is based at the Basil Hetzel Institute, The Queen Elizabeth Hospital. The BHI, TQEH is also where the CADOSA Management and Analytics Team are based, and it is this group who will oversee the data systems underpinning the PAMICO Project implementation and reporting across South Australian hospitals. The Coronary Angiogram Database of South Australia (CADOSA Registry) is a clinical quality registry that enrols every public hospital patient undergoing coronary angiography in South Australia. The registry currently includes over 60,000 South Australian patients. The CADOSA registry is managed by Associate Professor Rosanna Tavella, whose input to this application was essential to the success of this project according to lead investigator Professor John Beltrame.

The PAMICO Project will implement an innovative, holistic, patient-centred, integrated, personalised clinical quality care intervention strategy for Acute Myocardial Infarction (AMI) patients undergoing coronary angiography in the major public tertiary hospitals. It involves three objectives including deployment of integrated data management systems to provide personalised clinical pathways; assessing their impact on patient care with feedback to clinicians; and ensuring that recent Heart Attack Standards of Care are uniformly implemented within our hospitals.

In addition to the 3 year NHMRC funding, three partner organisations have pledged a combined total of $2,275,997 in cash and in-kind support to the project. They include:

  • Central Adelaide Local Health Network (CALHN) – which will have a lead role in designing and integrating personalised, risk-stratified management pathways into routine care for acute myocardial infarction (AMI) patients across SA Health,
  • SA Health – who will work with the project team to establish routine assessment of the Australian Commission on Safety and Quality in Health Care (ACSQHC) clinical indicators for AMI patients and support the integration of electronic data systems with the Health Outcomes Science technology solution, and
  • Health Outcomes Sciences – a technology partner who will guide the implementation of a novel technology solution to incorporate predictive analytics into routine clinical care of AMI patients to support improved clinical and financial performance.

The outcomes of the PAMICO Project are expected to have both national and international implications in the future management of acute heart attacks.

See also: https://www.adelaide.edu.au/newsroom/news/list/2021/03/29/heart-attack-research-receives-35million-boost

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