• About
  • People
  • Projects
  • Key Publications
  • Funding
  • Collaborations

The Respiratory Research Group is the research arm of The Queen Elizabeth Hospital’s Respiratory Medicine Unit and is involved in running a number of Clinical Trials and Investigator-led projects. The unit has a number of research studies underway addressing knowledge and practice gaps for prevalent respiratory conditions, including: chronic obstructive pulmonary disease (COPD), asthma, bronchiectasis, sleep apnoea, pneumonia, respiratory failure and smoking. Other key areas of research are non-invasive ventilation and intervention pulmonology and indigenous health.

Researchers

Additional Research Staff Members

NamePositionEmail address
Jonathon PolasekHead of TQEH Respiratory Medicine Unit, ClinicianJonathon.Polasek@sa.gov.au
Anil RoyClinicianAnil.Roy@sa.gov.au
Antony VealeClinicianAntony.Veale@sa.gov.au
Zafar UsmaniClinicianzafar.usmani@sa.gov.au
Andrew FonClinicianandrew.fon@sa.gov.au
Donna KeatleyPulmonary Function Test (PFT) Laboratory SupervisorDonna.Keatley@sa.gov.au
Pamela KiddPFT Laboratory Scientistpamela.kidd@sa.gov.au
Xiao Hui LiuPFT Laboratory TechnicianXiaoHui.Liu@sa.gov.au
Ryan MorenaPFT Laboratory TechnicianRyan.Morena@sa.gov.au

Student Alumni (since 2016)

NameDegreeYear AwardedThesis titleSupervisorsScholarship
Zoe KopsaftisPhD, The University of Adelaide2019, with Dean's commendation for doctoral thesis excellenceBest-Practice Evidence Based Medicine for the Effective Management of Chronic Obstructive Pulmonary Disease (COPD)

Nottle M, Phillips P, Carson-Chahhoud K Respiratory Medicine & Faculty of Health Sciences, University of Adelaide scholarship
Zafar UsmaniPhD, The University of Adelaide2018Treatment of anxiety among patients with Chronic Obstructive Pulmonary DiseaseSmith B, Esterman AJ
Charmaine KingHonours, The University of Adelaide2016The use of innovative technology to deliver health interventions for asthmaCarson K, Smith B and van Agteren JThe Hospital Research Foundation honours scholarship
Kristin CarsonPhD, The University of Adelaide2015, with Dean's commendation for doctoral thesis excellenceAdvancing treatment options for tobacco cessation, prevention and related illnesses, with particular reference to Indigenous populationsSmith B, Esterman A, Veale A and Peters MJ

 

In-hospital clinical trials
  • POC-study: Randomized Crossover Trial of portable oxygen cylinders versus battery powered portable oxygen concentrators
  • PAC-study: Paroxetine for Anxiety in Patients with Chronic Obstructive Pulmonary Disease.
  • STOP-project: The Smoking Termination Opportunity for inPatients project
  • NRT-study: Nicotine receptor up-regulation with transdermal nicotine patches
Models of Care
  • e-ACCORD: Advancing inpatient management of COPD through redesign & implementation of evidence-based guidelines for the management of COPD
  • South Australian Ambulance Service (SAAS) and Central Adelaide Local Health Network (CALHN), Chronic Obstructive Pulmonary Disease (COPD) at Home Service: Reducing avoidable hospital presentations
  • Efficacy of a Single-night Multiple-split Diagnostic and Therapy Assessment for Type II Respiratory Failure using Positive Airway Pressure and Supplemental Oxygen.
Smoking & Healthy Living
  • Indigenous tobacco cessation in adults and prevention amongst youth
  • Community and mass media interventions to prevent smoking in youth
  • Kick.it: the development of a social network-based smoking cessation platform for mobile devices.
  • Depression in Indigenous Populations
Cochrane reviews
  • Nurse-led care for the management of bronchiectasis
  • Aspiration v tube drainage for spontaneous pneumothorax
  • Home care outreach nursing in COPD
  • Gastro-oesophageal reflux treatment for asthma
  • Interventions for smoking cessation in Indigenous populations
  • Interventions for tobacco prevention in Indigenous youth
  • Psychological interventions for anxiety in COPD
  • Psychological interventions for depression in COPD
  • Pharmacological interventions for depression in COPD
  • Pharmacological interventions for anxiety in COPD
  • Prolonged antibiotics for bronchiectasis
  • Anticoagulants for idiopathic pulmonary fibrosis
  • Physical training for asthma
  • Lung Volume Reduction Surgery in Diffuse Emphysema
  • Minimally Invasive Techniques for Lung Volume Reduction in Severe Emphysema
  • Asthma-self management education with either regular healthcare professional review or written action plan or both for adults
  • Ambulatory oxygen for people with COPD who are not hypoxemic at rest
  • Community interventions for preventing smoking in young people
  • Mass media interventions for preventing smoking in young people
  • Training health professionals in smoking cessation
  • Community pharmacy personnel interventions for smoking cessation
  • Consumer guidelines for chronic disease management
  • Continuous positive airway pressure for obstructive sleep apnoea in adults
  • Non-invasive positive pressure ventilation for treatment of respiratory failure due to severe acute exacerbation of asthma
  • Non-invasive ventilation for the management of acute hypercapnic respiratory failure due to exacerbation of COPD
  • Nurse specialists care for bronchiectasis
  • Oxygen therapy in the pre-hospital setting for acute exacerbations of COPD
  • Prolonged antibiotics for non-cystic fibrosis bronchiectasis in children and adults
Qualitative exploration of experiences and perceptions relating to the provision of best-practice care for asthma in South Australia
Risk factors for asthma-related hospitalisation: multi-state case-control study
Varenicline and nicotine replacement therapy for smokers admitted to hospital (VANISH)
Smoking Termination Opportunity for inPatients (STOP): Superiority of a course of varenicline tartrate plus counselling over counselling alone for smoking cessation: A 12-month randomised controlled trial for inpatients

Smith BJ, Carson KV, Brinn MP, Labiszewski NA, Peters M, Fitridge R, Koblar S, Jannes J, Veale A, Goldsworthy S, Litt J, Edwards D, Esterman AJ. Smoking Termination Opportunity for inPatients (STOP): Superiority of a course of varenicline tartrate plus counselling over counselling alone for smoking cessation: A 12-month randomised controlled trial for inpatients. Thorax; 2013; 68(5): 485-6 

Pubmed Link:  https://www.ncbi.nlm.nih.gov/pubmed/22993168

Psychological therapies for the treatment of anxiety disorders in chronic obstructive pulmonary disease

Usmani ZA, Carson KV, Heslop K, Esterman AJ, De Soyza A, Smith BJ. Psychological therapies for the treatment of anxiety disorders in chronic obstructive pulmonary disease. Cochrane Database of Systematic Reviews; 2017 Mar 21;3:CD010673

Pubmed Link:  https://www.ncbi.nlm.nih.gov/pubmed/28322440

Interventions for smoking cessation in Indigenous populations

Carson KV, Brinn MP, Peters M, Veale A, Esterman AJ, Smith BJ. Interventions for smoking cessation in Indigenous populations. Cochrane Database of Systematic Reviews ; 2012 Jan 18;1:CD009046

Pubmed Link:  https://www.ncbi.nlm.nih.gov/pubmed/22258998

Safety of varenicline tartrate and counseling versus counseling alone for smoking cessation: a randomized controlled trial for inpatients (STOP study)

Carson KV, Smith BJ, Brinn MP, Peters MJ, Fitridge R, Koblar SA, Jannes J, Singh K, Veale AJ, Goldsworthy S, Litt J, Edwards D, Hnin KM, Esterman AJ. Safety of varenicline tartrate and counseling versus counseling alone for smoking cessation: a randomized controlled trial for inpatients (STOP study). Nicotine & Tobacco Research; 2014 Nov;16(11):1495-502

Pubmed Link:  https://www.ncbi.nlm.nih.gov/pubmed/25031315

COPD-X Australian and New Zealand guidelines for the diagnosis and management of chronic obstructive pulmonary disease: 2017 update

Yang IA, Brown JL, George J, Jenkins S, McDonald CF, McDonald VM, Phillips K, Smith BJ, Zwar NA, Dabscheck E. COPD-X Australian and New Zealand guidelines for the diagnosis and management of chronic obstructive pulmonary disease: 2017 update. Med J Aust.; 2017 Nov 20;207(10):436-442.

Pubmed Link:  https://www.ncbi.nlm.nih.gov/pubmed/29129177

Funding since 2010

Chief InvestigatorsGranting BodyProject TitleType of GrantTotal Grant AmountFunding Period
Carson-Chahhoud KV, Kopsaftis ZA, Sharrad KJ, Esterman ASax InstituteEvidence for smoking quitlinesCommissioned rapid review of evidence$25,0002018 - 2019
Johnson G, Abramson M, Dooley M, Bonevski B, Smith BJ, Webb APfizerVarenicline And Nicotine replacement therapy for Smokers admitted to Hospital (VANISH)Global Research Awards for Nicotine Dependence (GRAND)USD $200,0002018 - 2019
Smith B, Carson KV, Esterman A,
Peters M, Gould G
NHMRC (#1108309)
Training health professionals in tobacco
cessation and evidence translation for
Aboriginal Australians
Project grant$185,725 pa2016 - 2018
Kopsaftis ZA, van Agteren JV, Carson-Chahhoud KV, O'Loughlin T, Smith BAustralian and New Zealand School of GovernmentCessation for smokers seeking treatment and advice from health care professionals in the hospital setting$10,0002016 - 2017
Carson KVNHMRC (#1092680)
and Cancer
Australia (cofunded)
Translating Research into Practice
Fellowship
TRIP Fellowship$136,456 pa2015 - 2016
Van Agteren JEM, Smith BJThe Hospital Research Foundation (THRF)Kick.it: the development of a social network-based smoking cessation platform for mobile devices.THRF 50th Anniversary Awards$25,0002015
Carson KV, Smith BJNHMRCTraining Health Professionals in smoking cessation and tobacco abuse prevention for Aboriginal AustraliansTRIP Fellowship (Translating Research In to Practice)$172,9112014 - 2017
Carson KV, Smith BJCancer AustraliaTraining Health Professionals in smoking cessation and tobacco abuse prevention for Aboriginal AustraliansCo-funding for NHMRC TRIP Fellowship$100,0002014 - 2017
Carson KV, Smith BJThoracic Society of Australia and New Zealand (TSANZ)Training Health Professionals in smoking cessation and tobacco abuse prevention for Aboriginal AustraliansTSANZ Robert Pierce Grant-in-Aid$15,0002015 - 2016
Walters J, Walters H, Holland A, Yang I, Gibson P, Smith BJNHMRCAustralasian Satellite of the Cochrane Airways Group Centre for Research Excellence$69,0002013 - 2016
Carson KV, Peters M, Esterman AJ, Veale A, Smith BJAustralian and New Zealand School of GovernmentInterventions for smoking cessation and prevention in Indigenous populations $10,0002013 - 2015
Clifton V (Smith BJ Associate Investigator)NHMRCEffect of asthma during pregnancy on placenta and foetus $216,5502009 - 2011
Robertson M, Smith BJ, Robertson T, Carson K, Ward M The Hospital Research Foundation (THRF)Nicotine receptor up-regulation evaluation $20,0002010 - 2012

External Collaborations

CollaboratorInstitutionCityCountry
Adrian EstermanUniversity of South AustraliaAdelaideAustralia
Paddy PhillipsSA HealthAdelaideAustralia
Vicki CliftonMater UniversityBrisbaneAustralia
Lucy MorganConcord Repatriation General HospitalSydneyAustralia
Matthew PetersConcord Repatriation General HospitalSydneyAustralia
Peter WarkThe University of NewcastleNewcastleAustralia
Gillian GouldThe University of NewcastleNewcastleAustralia
Joep Van AgterenSAHMRIAdelaideAustralia
Kristin Carson-ChahhoudUniversity of South AustraliaAdelaideAustralia
Andrew TaiWomen's and Children's HospitalAdelaideAustralia
Johnson GeorgeMonash UniversityMelbourneAustralia
COPD-X Guidelines CommitteeLung Foundation AustraliaBrisbaneAustralia
Asthma FoundationAustralia
Fay Fuller FoundationAustralia